- APC Mutants
- APC-A
- APC-A cdh1∆
- APC-A cdh1∆ in galactose
- APC-A cdh1∆ GAL-SIC1
- APC-A cdh1∆ GAL-CDC6
- APC-A cdh1∆ multi-copy SIC1
- APC-A cdh1∆ multicopy CDC6
- APC-A cdh1∆ multicopy CDC20
- APC-A sic1∆
- APC-A sic1∆ cdc6∆2-49
- APC-A GAL-CLB2
- cln1∆ cln2∆ cln3∆ apc-ts
APC-A cdh1∆ multicopy CDC6
debug: ,
test user =
test db =
Simulation:
Change of parameters: ka20"=0, ksf6'=0.072, ksf6"=0.36, ksf6"'=0.012 (=3 copies), kscdh=0, init CDH1T=CDH1=0.
Experiments:
Cross, F.R. (2003). Two redundant oscillatory mechanisms in the yeast cell cycle. Dev. Cell 4:741-752.
[Abstract] [Article]
[Abstract] [Article]
Experimental results: Fig 4, rescued.
Comments: In our simulation, mass keeps increasing after each cycle and the cell eventually arrests after 5th cycle.
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